Antiviral activity of Rheum palmatum methanol extract and chrysophanol against Japanese encephalitis virus
نویسندگان
چکیده
منابع مشابه
Antiviral Activity of Isatis indigotica Extract and Its Derived Indirubin against Japanese Encephalitis Virus
Isatis indigotica is widely used in Chinese Traditional Medicine for clinical treatment of virus infection, tumor, and inflammation, yet its antiviral activities remain unclear. This study probed antiviral activity of I. indigotica extract and its marker compounds against Japanese encephalitis virus (JEV). I. indigotica methanol extract, indigo, and indirubin proved less cytotoxic than other co...
متن کاملAntiviral Activity of Baicalein and Quercetin against the Japanese Encephalitis Virus
Japanese encephalitis (JE), a mosquito-borne viral disease, is endemic to the entire east and southeast Asia, and some other parts of the world. Currently, there is no effective therapeutic available for JE; therefore, finding the effective antiviral agent against JEV replication is crucial. In the present study, the in vitro antiviral activity of baicalein and quercetin, two purportedly antivi...
متن کاملKaryotype analysis of Rheum palmatum.
Rheum palmatum, one of the source plants of the traditional Chinese medicine rhubarb, is anendemic and endangered species. To our knowledge, this is the first report on the chromosome number and karyotype of this species. Sectioning combined with micrography was used to analyze the karyotype. The following results were obtained: R. palmatum had a stable chromosome number 2n = 22; the basic numb...
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Mx proteins are interferon (IFN)-induced dynamin-like GTPases that are present in all vertebrates and inhibit the replication of myriad viruses. However, the role Mx proteins play in IFN-mediated suppression of Japanese encephalitis virus (JEV) infection is unknown. In this study, we set out to investigate the effects of Mx1 and Mx2 expression on the interferon-α (IFNα) restriction of JEV repli...
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Abstract: Influenza virus is the most important cause of annual morbidities and mortalities worldwide with numerous antigenic drifts and shifts. Inaccessibility to effective drugs and vaccines has made world health authorities to be interested in traditional medicine in order to prevent spread of the infectious agent. Garlic is one of the most famous of all plants in human history. It has bee...
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ژورنال
عنوان ژورنال: Archives of Pharmacal Research
سال: 2014
ISSN: 0253-6269,1976-3786
DOI: 10.1007/s12272-013-0325-x